Efficacy and safety of SPRINT and STAR protocol on Malaysian critically-ill patients

• Main Authors: Ahamad, Nurhamim, Abdul Razak, Normy Norfiza, Mohd Suhaimi, Fatanah, Jamaludin, Ummu Kulthum, Pretty, Christopher, Chase, James Geoffrey, Md Ralib, Azrina, Mat Nor, Mohd Basri
• Format: Book Section
• Language: English
• Published: IEEE 2016
• Subjects: RA440-440.87 Study and teaching. Research
• Online Access: http://eprints.usm.my/37329/1/efficacyofsprintandstar.pdf; http://eprints.usm.my/37329/; http://ieeexplore.ieee.org/abstract/document/7843476/
• Institution: Universiti Sains Malaysia

Abstract: Intensive care unit patients may have a better glycaemic management with the right control protocol. Results of virtual trial performance on Malaysian critically-ill patients adopting a model-derived and model-based control protocol known as SPRINT and STAR are presented in this paper. These ICU patients have been treated by intensive sliding-scale insulin infusion. The effectiveness and safety of glycaemic control are then analysed. Results showed that patient safety improved by 83% with SPRINT and STAR protocol as the number of hypoglycaemic patients significantly reduced (BG<;2.2 mmol/L). Percentage of time within desired bands and median BG improves in both SPRINT and STAR. However, the improvements are associated with higher number of BG measurements (workload).