Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives

Four different types of compounds were successfully synthesized and characterized. The syntheses of these compounds involved benzylation, addition elimination and cyclization reactions. The structures of the synthesized compounds were confirmed by melting points, FTIR, HRMS, 1D and 2D NMR spectrosco...

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Main Author:	al-Douh, Mohammed Hadi Saeed
Format:	Thesis
Language:	English
Published:	2010
Subjects:	QD1-999 Chemistry
Online Access:	http://eprints.usm.my/42063/1/MOHAMMED_HADI_SAEED_AL%E2%80%93DOUH.pdf http://eprints.usm.my/42063/
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Institution:	Universiti Sains Malaysia
Language:	English

id	my.usm.eprints.42063
record_format	eprints
spelling	my.usm.eprints.42063 http://eprints.usm.my/42063/ Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives al-Douh, Mohammed Hadi Saeed QD1-999 Chemistry Four different types of compounds were successfully synthesized and characterized. The syntheses of these compounds involved benzylation, addition elimination and cyclization reactions. The structures of the synthesized compounds were confirmed by melting points, FTIR, HRMS, 1D and 2D NMR spectroscopy and X–ray crystallography. The first type of these compounds is 2-benzyloxy-3- methoxybenzaldehyde 75, which was synthesized by the reaction of o-vanillin with benzyl bromide in acetone as the solvent and K2CO3 as a base in the presence of tetra-n-butylammonium iodide (TBAI) as catalyst. 2010 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/42063/1/MOHAMMED_HADI_SAEED_AL%E2%80%93DOUH.pdf al-Douh, Mohammed Hadi Saeed (2010) Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives. PhD thesis, Universiti Sains Malaysia.
institution	Universiti Sains Malaysia
building	Hamzah Sendut Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Sains Malaysia
content_source	USM Institutional Repository
url_provider	http://eprints.usm.my/
language	English
topic	QD1-999 Chemistry
spellingShingle	QD1-999 Chemistry al-Douh, Mohammed Hadi Saeed Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives
description	Four different types of compounds were successfully synthesized and characterized. The syntheses of these compounds involved benzylation, addition elimination and cyclization reactions. The structures of the synthesized compounds were confirmed by melting points, FTIR, HRMS, 1D and 2D NMR spectroscopy and X–ray crystallography. The first type of these compounds is 2-benzyloxy-3- methoxybenzaldehyde 75, which was synthesized by the reaction of o-vanillin with benzyl bromide in acetone as the solvent and K2CO3 as a base in the presence of tetra-n-butylammonium iodide (TBAI) as catalyst.
format	Thesis
author	al-Douh, Mohammed Hadi Saeed
author_facet	al-Douh, Mohammed Hadi Saeed
author_sort	al-Douh, Mohammed Hadi Saeed
title	Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives
title_short	Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives
title_full	Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives
title_fullStr	Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives
title_full_unstemmed	Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives
title_sort	synthesis, characterization and anti-proliferation study of some benzimidazole derivatives
publishDate	2010
url	http://eprints.usm.my/42063/1/MOHAMMED_HADI_SAEED_AL%E2%80%93DOUH.pdf http://eprints.usm.my/42063/
_version_	1643710400084049920

Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives

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