Immune checkpoint molecules and glucose metabolism in HIV-induced T cell exhaustion

• Main Authors: Chan, Yee Teng, Cheong, Heng Choon, Tang, Ting Fang, Rajasuriar, Reena, Cheng, Kian-Kai, Looi, Chung Yeng, Wong, Won Fen, Kamarulzaman, Adeeba
• Format: Article
• Language: English
• Published: MDPI 2022
• Subjects: TP Chemical technology
• Online Access: http://eprints.utm.my/id/eprint/101236/1/ChengKianKai2022_ImmuneCheckpointMoleculesandGlucoseMetabolism.pdf; http://eprints.utm.my/id/eprint/101236/; http://dx.doi.org/10.3390/biomedicines10112809
• Institution: Universiti Teknologi Malaysia

The progressive decline of CD8+ cytotoxic T cells in human immunodeficiency virus (HIV)-infected patients due to infection-triggered cell exhaustion and cell death is significantly correlated with disease severity and progression into the life-threatening acquired immunodeficiency syndrome (AIDS) st...