One-pot synthesis, molecular docking, ADMET, and DFT studies of novel pyrazolines as promising SARS-CoV-2 main protease inhibitors

One-pot synthesis, molecular docking, ADMET, and DFT studies of novel pyrazolines as promising SARS-CoV-2 main protease inhibitors

Pyrazoline and its derivatives have numerous prominent pharmacological effects. Focusing on its anti-viral property, we have designed and synthesized three novel pyrazoline derivatives (A1–A3) through one-pot three components and characterized them using different spectroscopic techniques (FT-IR, 1H...

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Bibliographic Details
Main Authors: Salih, Rezan Huseen Hama, Hasan, Aso Hameed, Hussein, Awaz Jamil, Samad, Mohammed Kareem, Shakya, Sonam, Jamalis, Joazaizulfazli, Hawaiz, Farouq Emam, Pratama, Mohammad Rizki Fadhil
Format: Article
Language:English
Published: Springer Science and Business Media B.V. 2022
Subjects:
QD Chemistry
Online Access:http://eprints.utm.my/103922/1/JoazaizulfazliJamalis2022_OnePotSynthesisMolecularDockingADMET.pdf
http://eprints.utm.my/103922/
http://dx.doi.org/10.1007/s11164-022-04831-5
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Institution: Universiti Teknologi Malaysia
Language: English

Internet

http://eprints.utm.my/103922/1/JoazaizulfazliJamalis2022_OnePotSynthesisMolecularDockingADMET.pdf
http://eprints.utm.my/103922/
http://dx.doi.org/10.1007/s11164-022-04831-5

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