Study on cannabidiol and pulse electric field on breast cancer cells

• Main Authors: Abdul Jamil, Muhammad Mahadi, Abd. Rahman, Nur Adilah, Adon, Mohd. Nazib, Ambar, Radzi, Javid, Farideh, Youseffi, Mansour, Saidin, Syafiqah
• Format: Conference or Workshop Item
• Published: American Chemical Society 2023
• Subjects: TK Electrical engineering. Electronics Nuclear engineering
• Online Access: http://eprints.utm.my/107611/; http://dx.doi.org/10.1109/CSPA57446.2023.10087551
• Institution: Universiti Teknologi Malaysia

Discovering a new cancer treatment Researchers are becoming more eager to uncover new medicinal compounds from living species. In the UK, CBD has been rising in demand as an alternative therapeutic agent and is used in various medicinal products. CBD, or cannabidiol, is a phytocannabinoid, one of the identified cannabinoids in cannabis plants. It doesn't contain tetrahydrocannabinol (THC), which is a psychoactive ingredient. While electroporation is one of the non-invasive techniques for nonviral delivery systems, such as molecule introduction and molecule transfer in a variety of sizes depending on the parameter chosen. The cell response to CBD compound combined with the electroporation method was the focus of this study. The findings demonstrated a positive response to the antiproliferative properties of cancer cells, and the treatment was further aided by a pulse electric field of 600 V/cm for 30µs with a single pulse. The results showed further decrements in cell viability. This finding may contribute toward cancer treatment as an adjunct alternative anticancer agent.