Diacerein-mediated inhibition of IL-6/IL-6R signaling induces apoptotic effects on breast cancer

Diacerein-mediated inhibition of IL-6/IL-6R signaling induces apoptotic effects on breast cancer

Interleukin-6 (IL-6) signaling network has been implicated in oncogenic transformations making it attractive target for the discovery of novel cancer therapeutics. In this study, potent antiproliferative and apoptotic effect of diacerein were observed against breast cancer. In vitro apoptosis was in...

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Bibliographic Details
Main Authors: Bharti, Rashmi, Dey, Goutam, Ojha, Probir kumar, Rajput, Shashi, Jaganathan, Saravana Kumar, Sen, Ramkrishna, Mandal, Mahitosh
Format: Article
Published: Nature Publishing Group 2016
Subjects:
RC Internal medicine
Online Access:http://eprints.utm.my/id/eprint/69208/
http://dx.doi.org/10.1038/onc.2015.466
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Institution: Universiti Teknologi Malaysia

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http://eprints.utm.my/id/eprint/69208/
http://dx.doi.org/10.1038/onc.2015.466

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