A Rational Workflow for Sequential Virtual Screening of Chemical Libraries on Searching for New Tyrosinase Inhibitors

• المؤلف الرئيسي: Le, Thi Thu Huong
• التنسيق: مقال
• اللغة: English
• منشور في: Bentham Science Publishers 2016
• الموضوعات: Drug-likenessfiltering; Molecular docking; QSAR modeling; Similarity searching; Tyrosinase inhibitor; Virtual screening
• الوصول للمادة أونلاين: http://repository.vnu.edu.vn/handle/VNU_123/11503
• المؤسسة: Vietnam National University, Hanoi

The tyrosinase is a bifunctional, copper-containing enzyme widely distributed in the phylogenetic tree. This en-zyme is involved in the production of melanin and some other pigments in humans, animals and plants, including skin pigmentations in mammals, and browning process in plants and vegetable...