Comparative Proteomics Reveals Anticancer Compounds from Lansium domesticum Against NSCLC Cells Target Mitochondrial Processes

• Main Authors: Alvarez, Michael Russelle, De Juan, Florence, Zhou, Qingwen, Dimzon, Ian Ken D, Grijaldo, Sheryl Joyce, Sunga, Sean, Heralde, Francisco, Lebrilla, Carlito B., Completo, Gladys Cherisse, Nacario, Ruel C.
• 格式: text
• 出版: Archīum Ateneo 2023
• 主題: Lansium domesticum; lung cancer; mitochondria; proteomics; Biochemistry; Biochemistry, Biophysics, and Structural Biology; Cancer Biology; Cell and Developmental Biology; Life Sciences
• 在線閱讀: https://archium.ateneo.edu/chemistry-faculty-pubs/203; https://doi.org/10.1002/cbf.3768

Lansium domesticum is identified as a potential source of anticancer compounds. However, there are minimal studies on its anti-lung cancer properties as well as its mechanism of action. Here, we show the specificity of lanzones hexane (LH) leaf extracts to non-small cell lung cancer cells (A549) com...