The molecular motor F-ATP synthase is targeted by the tumoricidal protein HAMLET

• المؤلفون الرئيسيون: Ho, James, Sielaff, Hendrik, Nadeem, Aftab, Svanborg, Catharina, Grüber, Gerhard
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2015
• الموضوعات: DRNTU::Science::Biological sciences::Molecular biology
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/100349; http://hdl.handle.net/10220/25684
• المؤسسة: Nanyang Technological University

HAMLET (human alpha-lactalbumin made lethal to tumor cells) interacts with multiple tumor cell compartments, affecting cell morphology, metabolism, proteasome function, chromatin structure and viability. This study investigated if these diverse effects of HAMLET might be caused, in part, by a direct...