Oocyte Factors Suppress Mitochondrial Polynucleotide Phosphorylase to Remodel the Metabolome and Enhance Reprogramming

Oocyte factors not only drive somatic cell nuclear transfer reprogramming but also augment the efficiency and quality of induced pluripotent stem cell (iPSC) reprogramming. Here, we show that the oocyte-enriched factors Tcl1 and Tcl1b1 significantly enhance reprogramming efficiency. Clonal analysis...

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Main Authors: Khaw, Swea-Ling, Koh, Cheng-Gee, Lim, Bing, Chua, Min-Wen, Ng, Shyh-Chang
其他作者: School of Biological Sciences
格式: Article
語言:English
出版: 2015
在線閱讀:https://hdl.handle.net/10356/103359
http://hdl.handle.net/10220/38738
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