QSAR for analogs of 1,5-N,N'-disubstituted-2-(substituted benzenesulphonyl) glutamamides as antitumor agents

• Main Authors: Panda, Parthasarathi, Samanta, Soma, Alam Sk, Mahasin, Basu, Soumya, Jha, Tarun
• 其他作者: School of Chemical and Biomedical Engineering
• 格式: Article
• 語言: English
• 出版: 2015
• 主題: DRNTU::Science::Biological sciences::Molecular biology
• 在線閱讀: https://hdl.handle.net/10356/104837; http://hdl.handle.net/10220/24712; http://www.researchgate.net/publication/230703410_QSAR_for_Analogs_of_15NN'Disubstituted2(substituted_benzenesulphonyl)_Glutamamides_as_Antitumor_Agents

Motivation. Cancer is a widespread and life threatening disease for which new and improved drugs are needed. It is well established that the transformation of the normal cells to a cancerous phenotype is often associated with cognate changes in the transport and metabolism of nutrients such as gluco...