Coupled mutations-enabled glycerol transportation in an aquaporin Z mutant

• المؤلفون الرئيسيون: Ping, Zhi, Zhou, Feng, Lin, Xin, Su, Haibin
• مؤلفون آخرون: Institute of Advanced Studies
• التنسيق: مقال
• اللغة: English
• منشور في: 2019
• الموضوعات: Aquaporin Z; Science::Biological sciences; Glycerol
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/106942; http://hdl.handle.net/10220/49662
• المؤسسة: Nanyang Technological University

Aquaporins are transmembrane channel proteins with key function being transportation of water or other small substrates. Escherichia coli Aqp Z transports water molecules only, whereas Glp F is permeable to glycerol. It is intriguing to explore the possibility to induce glycerol permeability in Aqp...