First genome-wide association study of latent autoimmune diabetes in adults reveals novel insights linking immune and metabolic diabetes

• المؤلفون الرئيسيون: Cousminer, Diana L., Ahlqvist, Emma, Mishra, Rajashree, Andersen, Mette K., Chesi, Alessandra, Hawa, Mohammad I., Davis, Asa, Hodge, Kenyaita M., Bradfield, Jonathan P., Zhou, Kaixin, Guy, Vanessa C., Åkerlund, Mikael, Wod, Mette, Fritsche, Lars G., Vestergaard, Henrik, Snyder, James, Højlund, Kurt, Linneberg, Allan, Käräjämäki, Annemari, Brandslund, Ivan, Kim, Cecilia E., Witte, Daniel, Sørgjerd, Elin Pettersen, Brillon, David J., Pedersen, Oluf, Beck-Nielsen, Henning, Grarup, Niels, Pratley, Richard E., Rickels, Michael R., Vella, Adrian, Ovalle, Fernando, Melander, Olle, Harris, Ronald I., Varvel, Stephen, Grill, Valdemar E. R., Hakonarson, Hakon, Froguel, Philippe, Lonsdale, John T., Mauricio, Didac, Schloot, Nanette C., Khunti, Kamlesh, Greenbaum, Carla J., Åsvold, Bjørn Olav, Yderstræde, Knud B., Pearson, Ewan R., Schwartz, Stanley, Voight, Benjamin F., Hansen, Torben, Tuomi, Tiinamaija, Boehm, Bernhard Otto, Groop, Leif, Leslie, R David, Grant, Struan F. A.
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2020
• الموضوعات: Science::Medicine; Latent Autoimmune Diabetes; Genetic
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/136698
• المؤسسة: Nanyang Technological University

OBJECTIVE Latent autoimmune diabetes in adults (LADA) shares clinical features with both type 1 and type 2 diabetes; however, there is ongoing debate regarding the precise definition of LADA. Understanding its genetic basis is one potential strategy to gain insight into appropriate classification of...