Computational discovery of vaccine targets

• المؤلف الرئيسي: Zhang, Guang Lan
• مؤلفون آخرون: Kwoh Chee Keong
• التنسيق: Theses and Dissertations
• اللغة: English
• منشور في: 2008
• الموضوعات: DRNTU::Engineering::Computer science and engineering::Computer applications::Life and medical sciences
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/14139

Epitope-based vaccines show great potential in fighting infectious diseases as well as non-communicable diseases. The identification of T-cell epitopes, a crucial step in the design of epitope-based vaccines, is a highly combinatorial problem. Peptide binding to major histocompatibility complex (MHC...