Exploring extracellular vesicles biogenesis in hypothalamic cells through a heavy isotope pulse/trace proteomic approach

• Main Authors: Tan, Chee Fan, Teo, Hui San, Park, Jung Eun, Dutta, Bamaprasad, Tse, Shun Wilford, Leow, Melvin Khee-Shing, Wahli, Walter, Sze, Siu Kwan
• 其他作者: School of Biological Sciences
• 格式: Article
• 語言: English
• 出版: 2020
• 主題: Science::Medicine; Extracellular Vesicles; Extracellular Vesicles Biogenesis
• 在線閱讀: https://hdl.handle.net/10356/144746
• 機構: Nanyang Technological University

Studies have shown that the process of extracellular vesicles (EVs) secretion and lysosome status are linked. When the lysosome is under stress, the cells would secrete more EVs to maintain cellular homeostasis. However, the process that governs lysosomal activity and EVs secretion remains poorly de...