Engineered lysins with customized lytic activities against enterococci and staphylococci

• المؤلفون الرئيسيون: Hana Sakina Muhammad Jai, Dam, Linh Chi, Tay, Lowella Servito, Koh, Jodi Jia Wei, Loo, Hooi Linn, Kline, Kimberly A., Goh, Boon Chong
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2021
• الموضوعات: Science::Biological sciences; Lysin; Enterococcus
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/145740

The emergence of multidrug-resistant bacteria has made minor bacterial infections incurable with many existing antibiotics. Lysins are phage-encoded peptidoglycan hydrolases that have demonstrated therapeutic potential as a novel class of antimicrobials. The modular architecture of lysins enables th...