Super-hydrophilic zwitterionic polymer surface modification facilitates liquid transportation of microfluidic sweat sensors
The transportation of sweat in an epidermal sweat sensor is critical for the monitoring of biochemical compositions of human sweat. However, it is still a challenge to engineer microfluidic devices with super-wetting channels for such epidermal sweat sensors. Herein, we report a zwitterionic poly (2...
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sg-ntu-dr.10356-1560762023-07-14T16:04:56Z Super-hydrophilic zwitterionic polymer surface modification facilitates liquid transportation of microfluidic sweat sensors Fu, Fanfan Wang, Jilei Tan, Yurong Yu, Jing School of Materials Science and Engineering Engineering::Materials Flexible Sweat Sensors Microfluidic Devices The transportation of sweat in an epidermal sweat sensor is critical for the monitoring of biochemical compositions of human sweat. However, it is still a challenge to engineer microfluidic devices with super-wetting channels for such epidermal sweat sensors. Herein, we report a zwitterionic poly (2-methacryloyloxyethyl phosphorylcholine) (PMPC) modified microfluidic device with super-wetting and good liquid transport ability via an azo coupling reaction of PMPC onto the surface of polydimethylsiloxane (PDMS) microfluidic devices. The obtained PMPC modified microfluidic device can be integrated with flexible electrochemical sensor to measure the ion compositions of human sweat in real-time. The super-hydrophilic zwitterionic polymer surface modification can greatly facilitate the transportation of body fluids in microfluidic sensors for the detection of various biomarkers. Such microfluidic sensors have great potential for next generation personalized healthcare. National Research Foundation (NRF) Submitted/Accepted version F.F., J.W., Y.T., and J.Y. acknowledge the AME programmatic fundingscheme of Cyber Physiochemical Interfaces (CPI) project #A18A1b0045and the Singapore National Research Fellowship (NRF-NRFF11-2019-0004). 2022-04-05T04:15:45Z 2022-04-05T04:15:45Z 2022 Journal Article Fu, F., Wang, J., Tan, Y. & Yu, J. (2022). Super-hydrophilic zwitterionic polymer surface modification facilitates liquid transportation of microfluidic sweat sensors. Macromolecular Rapid Communication, 43(5), 2100776-. https://dx.doi.org/10.1002/marc.202100776 1022-1336 https://hdl.handle.net/10356/156076 10.1002/marc.202100776 5 43 2100776 en #A18A1b0045 NRF-NRFF11-2019-0004 Macromolecular Rapid Communication This is the peer reviewed version of the following article: Fu, F., Wang, J., Tan, Y. & Yu, J. (2022). Super-hydrophilic zwitterionic polymer surface modification facilitates liquid transportation of microfluidic sweat sensors. Macromolecular Rapid Communication, 43(5), 2100776, which has been published in final form at https://doi.org/10.1002/marc.202100776. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. application/pdf |
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Engineering::Materials Flexible Sweat Sensors Microfluidic Devices Fu, Fanfan Wang, Jilei Tan, Yurong Yu, Jing Super-hydrophilic zwitterionic polymer surface modification facilitates liquid transportation of microfluidic sweat sensors |
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The transportation of sweat in an epidermal sweat sensor is critical for the monitoring of biochemical compositions of human sweat. However, it is still a challenge to engineer microfluidic devices with super-wetting channels for such epidermal sweat sensors. Herein, we report a zwitterionic poly (2-methacryloyloxyethyl phosphorylcholine) (PMPC) modified microfluidic device with super-wetting and good liquid transport ability via an azo coupling reaction of PMPC onto the surface of polydimethylsiloxane (PDMS) microfluidic devices. The obtained PMPC modified microfluidic device can be integrated with flexible electrochemical sensor to measure the ion compositions of human sweat in real-time. The super-hydrophilic zwitterionic polymer surface modification can greatly facilitate the transportation of body fluids in microfluidic sensors for the detection of various biomarkers. Such microfluidic sensors have great potential for next generation personalized healthcare. |
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School of Materials Science and Engineering |
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School of Materials Science and Engineering Fu, Fanfan Wang, Jilei Tan, Yurong Yu, Jing |
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Article |
author |
Fu, Fanfan Wang, Jilei Tan, Yurong Yu, Jing |
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Fu, Fanfan |
title |
Super-hydrophilic zwitterionic polymer surface modification facilitates liquid transportation of microfluidic sweat sensors |
title_short |
Super-hydrophilic zwitterionic polymer surface modification facilitates liquid transportation of microfluidic sweat sensors |
title_full |
Super-hydrophilic zwitterionic polymer surface modification facilitates liquid transportation of microfluidic sweat sensors |
title_fullStr |
Super-hydrophilic zwitterionic polymer surface modification facilitates liquid transportation of microfluidic sweat sensors |
title_full_unstemmed |
Super-hydrophilic zwitterionic polymer surface modification facilitates liquid transportation of microfluidic sweat sensors |
title_sort |
super-hydrophilic zwitterionic polymer surface modification facilitates liquid transportation of microfluidic sweat sensors |
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2022 |
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https://hdl.handle.net/10356/156076 |
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1773551403056234496 |