High expression of G6PD increases doxorubicin resistance in triple negative breast cancer cells by maintaining GSH level

• المؤلفون الرئيسيون: Luo, Man, Fu, Afu, Wu, Renfei, Wei, Na, Song, Kai, Lim, Sierin, Luo, Kathy Qian
• مؤلفون آخرون: Interdisciplinary Graduate School (IGS)
• التنسيق: مقال
• اللغة: English
• منشور في: 2022
• الموضوعات: Engineering::Bioengineering; Triple Negative Breast Cancer; Metastasis
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/161346

Resistance to doxorubicin (DOX) remains a big challenge to breast cancer treatment especially for triple negative breast cancer (TNBC). Our previous study revealed that the antioxidant system plays an important role in conferring metastasis derived DOX resistance. In this study, we used two-dimensio...