GRAMD1-mediated accessible cholesterol sensing and transport

• المؤلفون الرئيسيون: Naito, Tomoki, Saheki, Yasunori
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2022
• الموضوعات: Science::Medicine; Phosphatidylserine; Non-Vesicular Lipid Transport
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/162676
• المؤسسة: Nanyang Technological University

Cholesterol, an essential lipid for cell signaling and structural integrity of cellular membranes, is highly enriched in the plasma membrane (PM). However, the regulatory mechanisms that control its biosynthesis and uptake both reside in the endoplasmic reticulum (ER). Thus, the ER needs to constant...