Selective one-pot cascade synthesis of N-substituted highly functionalized pyrroles from unprotected sugars, primary amines, and oxoacetonitriles

• المؤلفون الرئيسيون: Xia, Mengxin, Lambu, Mallikharjuna Rao, Judeh, Zaher M. A.
• مؤلفون آخرون: School of Chemical and Biomedical Engineering
• التنسيق: مقال
• اللغة: English
• منشور في: 2022
• الموضوعات: Engineering::Chemical engineering; Cascade Reactions; Embeddings
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/163328

A one-pot, three-component cascade reaction between unprotected sugars, primary amines, and 3-oxoacetonitriles gave N-substituted 2,3,5-functionalized pyrroles or N-substituted 2,3,4-functionalized pyrroles in excellent yields and selectivities. The selectivity of the reaction was achieved by simple...