Refolding of full-length alpha-fetoprotein (F-AFP).

• 主要作者: Chandra, Kelvin.
• 其他作者: Susanna Leong Su Jan
• 格式: Final Year Project
• 語言: English
• 出版: 2009
• 主題: DRNTU::Engineering::Chemical engineering::Biotechnology
• 在線閱讀: http://hdl.handle.net/10356/16400
• 機構: Nanyang Technological University

Alpha-fetoprotein (AFP) is a promising polypeptide for the treatment of several autoimmune diseases. The denatured-reduced recombinant human (rhAFP) was successfully refolded previously by dilution and dialysis refolding. However, the refolding of the denatured-reduced full-length AFP (FL-AFP) with...