High levels of progesterone receptor B in MCF-7 cells enable radical anti-tumoral and anti-estrogenic effect of progestin

• المؤلفون الرئيسيون: Bajalovic, Natasa, Or, Yu Zuan, Woo, Amanda Rui En, Lee, Shi Hao, Lin, Valerie Chun Ling
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2023
• الموضوعات: Science::Biological sciences; Progestin; Progesterone Receptor
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/164807
• المؤسسة: Nanyang Technological University

The widely reported conflicting effects of progestin on breast cancer suggest that the progesterone receptor (PR) has dual functions depending on the cellular context. Cell models that enable PR to fully express anti-tumoral properties are valuable for the understanding of molecular determinant(s) o...