On the prediction of protein-ligand structural complexes and binding affinities by hybrid statistical scoring function

• المؤلف الرئيسي: Oon, Yu Yang
• مؤلفون آخرون: Mu Yuguang
• التنسيق: Final Year Project
• اللغة: English
• منشور في: Nanyang Technological University 2023
• الموضوعات: Science::Physics; Science::Biological sciences::Biophysics
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/166416

Computer-aided drug discovery has truly revolutionised the way we think about and how we develop new drugs targeted to treat obnoxious diseases. Among all the computational methods, scoring functions play a fundamental role in virtual screening, in which we screen through large chemical databases to...