Pluripotent stem cell-derived committed cardiac progenitors remuscularize damaged ischemic hearts and improve their function in pigs

• المؤلفون الرئيسيون: Yap, Lynn, Chong, Li Yen, Tan, Clarissa, Adusumalli, Swarnaseetha, Seow, Millie, Guo, Jing, Cai, Zuhua, Loo, Sze Jie, Lim, Eric, Tan, Ru San, Grishina, Elina, Soong, Poh Loong, Lath, Narayan, Ye, Lei, Petretto, Enrico, Tryggvason, Karl
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2023
• الموضوعات: Science::Medicine; Cardiac Progenitors; Heart Muscles
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/169965

Ischemic heart disease, which is often associated with irreversibly damaged heart muscle, is a major global health burden. Here, we report the potential of stem cell-derived committed cardiac progenitors (CCPs) have in regenerative cardiology. Human pluripotent embryonic stem cells were differentiat...