The complex proteolipidic behavior of the SARS-CoV-2 envelope protein channel: weak selectivity and heterogeneous oligomerization

• Main Authors: Surya, Wahyu, Tavares-Neto, Ernesto, Sanchis, Andrea, Queralt-Martín, María, Alcaraz, Antonio, Torres, Jaume, Aguilella, Vicente M.
• 其他作者: School of Biological Sciences
• 格式: Article
• 語言: English
• 出版: 2023
• 主題: Science::Biological sciences; Analytical Ultracentrifugation; Envelope Protein
• 在線閱讀: https://hdl.handle.net/10356/171023

The envelope (E) protein is a small polypeptide that can form ion channels in coronaviruses. In SARS coronavirus 2 (SARS-CoV-2), the agent that caused the recent COVID-19 pandemic, and its predecessor SARS-CoV-1, E protein is found in the endoplasmic reticulum-Golgi intermediate compartment (ERGIC),...