Metal-free synthesis of 3,3′-bisindolylmethanes in water using Ph₃C⁺[B(C₆F₅)₄]⁻as the pre-catalyst

• Main Authors: Zhang, Zhenguo, Ji, Liang, Liu, Xiaoxiao, Li, Zhihong, Lv, Yongheng, Jia, Zhenhua, Loh, Teck-Peng
• 其他作者: School of Physical and Mathematical Sciences
• 格式: Article
• 語言: English
• 出版: 2023
• 主題: Science::Chemistry; Catalytic Species; Friedel-Crafts
• 在線閱讀: https://hdl.handle.net/10356/171495

Here, we report a highly efficient catalytic species generated from Ph3C+[B(C6F5)4]− by the water mediated Friedel-Crafts type reaction of indoles with carbonyl compounds to afford 3,3′-bisindolylmethanes (BIMs). This scalable method is applicable to a wide variety of carbonyl compounds, including u...