RNA is a key component of extracellular DNA networks in Pseudomonas aeruginosa biofilms

• Main Authors: Mugunthan, Sudarsan, Wong, Lan Li, Winnerdy, Fernaldo Richtia, Summers, Stephen, Muhammad Hafiz Bin Ismail, Foo, Yong Hwee, Jaggi, Tavleen Kaur, Meldrum, Oliver W., Tiew, Pei Yee, Chotirmall, Sanjay Haresh, Rice, Scott A., Phan, Anh Tuân, Kjelleberg, Staffan, Seviour, Thomas
• 其他作者: Lee Kong Chian School of Medicine (LKCMedicine)
• 格式: Article
• 語言: English
• 出版: 2024
• 主題: Science::Biological sciences; Pseudomonas Aeruginosa; Biofilm
• 在線閱讀: https://hdl.handle.net/10356/172993

The extracellular matrix of bacterial biofilms consists of diverse components including polysaccharides, proteins and DNA. Extracellular RNA (eRNA) can also be present, contributing to the structural integrity of biofilms. However, technical difficulties related to the low stability of RNA make it d...