First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure

First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure

Diminished hepatocyte regeneration is a key feature of acute and chronic liver diseases and after extended liver resections, resulting in the inability to maintain or restore a sufficient functional liver mass. Therapies to restore hepatocyte regeneration are lacking, making liver transplantation th...

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書目詳細資料
Main Authors:	Zwirner, Stefan, Rmilah, Anan A. Abu, Klotz, Sabrina, Pfaffenroth, Bent, Kloevekorn, Philip, Moschopoulou, Athina A., Schuette, Svenja, Haag, Mathias, Selig, Roland, Li, Kewei, Zhou, Wei, Nelson, Erek, Poso, Antti, Chen, Harvey, Amiot, Bruce, Jia, Yao, Minshew, Anna, Michalak, Gregory, Cui, Wei, Rist, Elke, Longerich, Thomas, Jung, Birgit, Felgendreff, Philipp, Trompak, Omelyan, Premsrirut, Prem K., Gries, Katharina, Muerdter, Thomas E., Heinkele, Georg, Wuestefeld, Torsten, Shapiro, David, Weissbach, Markus, Koenigsrainer, Alfred, Sipos, Bence, Ab, Eiso, Zacarias, Magdalena Ortiz, Theisgen, Stephan, Gruenheit, Nicole, Biskup, Saskia, Schwab, Matthias, Albrecht, Wolfgang, Laufer, Stefan, Nyberg, Scott, Zender, Lars
其他作者:	School of Biological Sciences
格式:	Article
語言:	English
出版:	2024
主題:	Medicine, Health and Life Sciences Drug discovery and development Liver failure
在線閱讀:	https://hdl.handle.net/10356/178695
標簽:	添加標簽沒有標簽, 成為第一個標記此記錄!

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