In silico drug discovery for potential epidermal growth factor receptor agonists

• المؤلف الرئيسي: Han, Hao
• مؤلفون آخرون: Mu Yuguang
• التنسيق: Thesis-Master by Research
• اللغة: English
• منشور في: Nanyang Technological University 2024
• الموضوعات: Medicine, Health and Life Sciences; In silico; Molecular dynamics simulation; Epidermal growth factor receptor
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/178943

This study presents a novel approach in the field of in silico drug discovery, targeting the Epidermal Growth Factor Receptor (EGFR) to identify potential agonists. Utilizing structure-based virtual screening, the research identifies small molecules capable of binding to EGFR's extracellular do...