Control design for regulation of blood pressure during postoperative hypertension

• Main Author: Meng, Xianghong.
• Other Authors: Zhu, Kuanyi
• Format: Theses and Dissertations
• Published: 2008
• Subjects: DRNTU::Engineering::Electrical and electronic engineering::Control and instrumentation::Medical electronics
• Online Access: http://hdl.handle.net/10356/4889
• Institution: Nanyang Technological University

In special intensive care environments, automatic control could potentially be a cost effective solution for improving patient monitoring system. Postsurgical hy-pertension causing increase in blood pressure may occur in adult cardiac patients. Blood pressure can be quickly lowered in most patients by continuously infusing vasodilator drugs such as sodium nitroprusside (SNP). The rate of drug infusion is critical, hence requires close attention and frequent adjustment. Manual control by clinical personnel can be very tedious, time consuming and inconsistent. Great caution is required to handle the wide range of sensitivities to the drug, and over-dose of drug could cause serious toxic side effects on the patient. Therefore, there is a need to devise methods such as using control algorithms that can effectively regulate the drugs automatically. In this project, we propose some methods to adapt to different sensitivities and to regulate the desired MAP.