Conjugation of antibody fragments to ferritin protein cage for targeted delivery to cancer cells.
Ferritin is engineered as a targeted carrier for therapeutic and diagnostic agents. It is a naturally occurring biomaterial and functions in iron homeostasis in various organisms. The ferritin in this study is a protein cage derived from an archaeon Archaeoglobus fulgidus with unique self-assembling...
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| 格式: | Theses and Dissertations |
| 語言: | English |
| 出版: |
2012
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| 在線閱讀: | http://hdl.handle.net/10356/50532 |
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| 機構: | Nanyang Technological University |
| 語言: | English |