Elucidation of the chondrogenic gene regulatory network controlling embryonic skeletal development.
More than 90% of the skeleton in the developing mammalian embryo is formed via endochondral ossification which requires an obligatory cartilage intermediate as a template for bone formation, making chondrogenesis an essential pathway during development. Sox5, Sox6, and Sox9 were uncovered via class...
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| Format: | Theses and Dissertations |
| Language: | English |
| Published: |
2012
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| Online Access: | http://hdl.handle.net/10356/50735 |
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| Institution: | Nanyang Technological University |
| Language: | English |