Contribution of lung migratory dendritic cells to the generation of influenza immunity

• المؤلف الرئيسي: Ng, See Liang
• مؤلفون آخرون: Klaus Erik Karjalainen
• التنسيق: Theses and Dissertations
• اللغة: English
• منشور في: 2015
• الموضوعات: DRNTU::Science::Biological sciences
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/62214
• المؤسسة: Nanyang Technological University

Owing to the functional heterogeneity of DCs in the lung, there is a need to unravel the in vivo contribution of various DC subpopulations to the generation of influenza immunity. Using our Clec9a-DTR and Clec4a4-DTR transgenic mouse models which allow us to specifically deplete CD103+ cDCs and CD24...