Unravelling genetic heterogeneity of hepatocellular carcinoma with driver genes and subclones

• المؤلف الرئيسي: Ng, Ming Hwee
• مؤلفون آخرون: Zhai Wei Wei
• التنسيق: Final Year Project
• اللغة: English
• منشور في: 2015
• الموضوعات: DRNTU::Science::Biological sciences
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/65645

Integration of genetic studies in hepatocellular carcinoma (HCC) is lacking though its mortality rate has risen to the second highest. With 1186 samples from varying ethnicities, this study had collected the largest sample size to compile a catalog of HCC cancer genes with MutSigCV and 37 novel gene...