Biochemical and structural analysis of shelterin subcomplexes

• المؤلف الرئيسي: Inian, Oviya
• مؤلفون آخرون: Daniela Rhodes
• التنسيق: Theses and Dissertations
• اللغة: English
• منشور في: 2018
• الموضوعات: DRNTU::Science::Biological sciences
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/75683
• المؤسسة: Nanyang Technological University

Telomeric chromatin consists of tandem ‘TTAGGG’ DNA repeats that associate with a telomere-specific complex, known as shelterin. Shelterin has an indispensable role in telomere length homeostasis and protection against genomic instability arising from erroneous DNA damage responses. Shelterin collec...