Impact of Pparβ/δ deletion in non-parenchymal cells - liver physiology and disease (NAFLD)

• المؤلف الرئيسي: Chen, Kelvin Jiapeng
• مؤلفون آخرون: Tan Nguan Soon, Andrew
• التنسيق: Theses and Dissertations
• اللغة: English
• منشور في: 2018
• الموضوعات: DRNTU::Science::Biological sciences::Molecular biology
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/75912
• المؤسسة: Nanyang Technological University

Non-alcoholic fatty liver disease (NAFLD) is causing an alarming health issue in developed countries. NAFLD can progress from steatosis to non-alcoholic steatohepatitis (NASH) characterized by liver inflammation, leading to cirrhosis and hepatocellular carcinoma (HCC). Mice with impaired macrophage...