c-rel regulates Ezh2 expression in activated lymphocytes and malignant lymphoid cells

• المؤلفون الرئيسيون: Lim, Jun Feng, Grumont, Raelene, Gerondakis, Steve, Su, I-hsin, Neo, Wen Hao
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2015
• الموضوعات: DRNTU::Science::Biological sciences::Biochemistry
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/79473; http://hdl.handle.net/10220/25127
• المؤسسة: Nanyang Technological University

The polycomb group protein Ezh2 is a histone methyltransferase that modifies chromatin structure to alter gene expression during embryonic development, lymphocyte activation, and tumorigenesis. The mechanism by which Ezh2 expression is regulated is not well defined. In the current study, we report t...