Caveolae provide a specialized membrane environment for respiratory syncytial virus assembly

• Main Authors: Ravi, Laxmi Iyer, Huan, Tan Boon, Ludwig, Alexander, Nguyen, Tra Huong, Leong, Daniel, Sandin, Sara, Sugrue, Richard J.
• 其他作者: School of Biological Sciences
• 格式: Article
• 語言: English
• 出版: 2017
• 主題: Caveolin; Caveolae
• 在線閱讀: https://hdl.handle.net/10356/80921; http://hdl.handle.net/10220/43442
• 機構: Nanyang Technological University

Respiratory syncytial virus (RSV) is an enveloped virus that assembles into filamentous virus particles on the surface of infected cells. Morphogenesis of RSV is dependent upon cholesterol-rich (lipid raft) membrane microdomains, but the specific role of individual raft molecules in RSV assembly is...