Development of immune-modulatory RNAS to regulate RIG-I-like receptors mediated antiviral immune response for therapy and vaccination

• المؤلف الرئيسي: Yong, Hui Yee
• مؤلفون آخرون: Luo Dahai
• التنسيق: Theses and Dissertations
• اللغة: English
• منشور في: 2019
• الموضوعات: DRNTU::Science::Biological sciences
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/81015; http://hdl.handle.net/10220/47467
• المؤسسة: Nanyang Technological University

Retinoic Acid-Inducible Gene I (RIG-I) is a cytosolic pattern recognition receptor (PRR) involved in initiating host defence response against viruses. RIG-I distinguishes between self and foreign nucleic acids by recognising chemical features not found in endogenous cytoplasmic RNA. RIG-I exhibits...