Development of immune-modulatory RNAS to regulate RIG-I-like receptors mediated antiviral immune response for therapy and vaccination
Retinoic Acid-Inducible Gene I (RIG-I) is a cytosolic pattern recognition receptor (PRR) involved in initiating host defence response against viruses. RIG-I distinguishes between self and foreign nucleic acids by recognising chemical features not found in endogenous cytoplasmic RNA. RIG-I exhibits...
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| 格式: | Theses and Dissertations |
| 語言: | English |
| 出版: |
2019
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| 主題: | |
| 在線閱讀: | https://hdl.handle.net/10356/81015 http://hdl.handle.net/10220/47467 |
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| 機構: | Nanyang Technological University |
| 語言: | English |