Zika vaccines and therapeutics: landscape analysis and challenges ahead

• المؤلفون الرئيسيون: Wilder-Smith, Annelies, Vannice, Kirsten, Durbin, Anna, Hombach, Joachim, Thomas, Stephen J., Thevarjan, Irani, Simmons, Cameron P.
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2018
• الموضوعات: Zika Vaccines; Zika
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/81251; http://hdl.handle.net/10220/45067

Background Various Zika virus (ZIKV) vaccine candidates are currently in development. Nevertheless, unique challenges in clinical development and regulatory pathways may hinder the licensure of high-quality, safe, and effective ZIKV vaccines. Discussion Implementing phase 3 efficacy trials wi...