Synthetic and natural Peroxisome Proliferator-Activated Receptor (PPAR) agonists as candidates for the therapy of the metabolic syndrome

• المؤلفون الرئيسيون: Tan, Chek Kun, Zhuang, Yan, Wahli, Walter
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2017
• الموضوعات: Agonists; Peroxisome Proliferator-Activated Receptors
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/83609; http://hdl.handle.net/10220/42711

INTRODUCTION: Peroxisome proliferator-activated receptors (PPARs) are the molecular targets of hypolipidemic and insulin-sensitizing drugs and implicated in a multitude of processes that fine-tune the functions of all organs in vertebrates. As transcription factors they sense endogenous and exogenou...