The ciliopathy protein TALPID3/KIAA0586 acts upstream of Rab8 activation in zebrafish photoreceptor outer segment formation and maintenance

• المؤلفون الرئيسيون: Naharros, Irene Ojeda, Cristian, Flavia B., Zang, Jingjing, Gesemann, Matthias, Neuhauss, Stephan C. F., Bachmann-Gagescu, Ruxandra, Ingham, Philip William
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2018
• الموضوعات: Ciliopathies; Photoreceptors (PRs)
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/87542; http://hdl.handle.net/10220/45410

Ciliopathies are human disorders caused by dysfunction of primary cilia, ubiquitous microtubule-based organelles involved in signal transduction. Cilia are anchored inside the cell through basal bodies (BBs), modified centrioles also acting as microtubule-organization centers. Photoreceptors (PRs) a...