Guidelines for morpholino use in zebrafish

• المؤلفون الرئيسيون: Stainier, Didier Y. R., Raz, Erez, Meng, Anming, Mochizuki, Naoki, Ingham, Philip William, Schulte-Merker, Stefan, Yelon, Deborah, Weinstein, Brant M., Mullins, Mary C., Wilson, Stephen W., Ramakrishnan, Lalita, Amacher, Sharon L., Neuhauss, Stephan C. F., Panula, Pertti, Moens, Cecilia B., Lawson, Nathan D., Ekker, Stephen C., Burdine, Rebecca D., Eisen, Judith S.
• مؤلفون آخرون: Barsh, Gregory S.
• التنسيق: مقال
• اللغة: English
• منشور في: 2018
• الموضوعات: Zebrafish; DRNTU::Science::Medicine; Morpholino Oligonucleotide
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/88390; http://hdl.handle.net/10220/45729
• المؤسسة: Nanyang Technological University

The zebrafish (Danio rerio) has emerged as a powerful model to study vertebrate development and disease. Its short generation time makes it amenable to genetic manipulation and analysis, and its small size and high fecundity make it especially well suited for large-scale forward genetic and chemical screens. Fast-developing zebrafish embryos are transparent, facilitating live imaging of a variety of developmental processes in wild-type and mutant animals.