Cell-based high-throughput compound screening reveals functional interaction between oncofetal HMGA2 and topoisomerase I
HMGA2 is an important chromatin factor that interacts with DNA via three AT-hook domains, thereby regulating chromatin architecture and transcription during embryonic and fetal development. The protein is absent from differentiated somatic cells, but aberrantly re-expressed in most aggressive human...
Saved in:
| Main Authors: | , , , |
|---|---|
| 其他作者: | |
| 格式: | Article |
| 語言: | English |
| 出版: |
2018
|
| 主題: | |
| 在線閱讀: | https://hdl.handle.net/10356/88392 http://hdl.handle.net/10220/45779 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|