3D correlative electron microscopy reveals continuity of Brucella-containing vacuoles with the endoplasmic reticulum

• المؤلفون الرئيسيون: Sedzicki, Jaroslaw, Tschon, Therese, Low, Shyan Huey, Willemart, Kevin, Goldie, Kenneth N., Letesson, Jean-Jacques, Stahlberg, Henning, Dehio, Christoph
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2018
• الموضوعات: Endoplasmic Reticulum; Replicative Brucella-containing Vacuole
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/88621; http://hdl.handle.net/10220/44669
• المؤسسة: Nanyang Technological University

Entry of the facultative intracellular pathogen Brucella into host cells results in the formation of endosomal Brucella-containing vacuoles (eBCVs) that initially traffic along the endocytic pathway. eBCV acidification triggers the expression of a type IV secretion system that translocates bacterial...