Mechanistic insights into PTS2-mediated peroxisomal protein import : the co-receptor PEX5L drastically increases the interaction strength between the cargo protein and the receptor PEX7

• المؤلفون الرئيسيون: Kunze, Markus, Wiesinger, Christoph, Schmid, Johannes A., Berger, Johannes, Malkani, Naila, Maurer-Stroh, Sebastian
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2018
• الموضوعات: DRNTU::Science::Biological sciences; Conformational Change; Peroxisome
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/88962; http://hdl.handle.net/10220/46061
• المؤسسة: Nanyang Technological University

The destination of peroxisomal matrix proteins is encoded by short peptide sequences, which have been characterized as peroxisomal targeting signals (PTS) residing either at the C terminus (PTS1) or close to the N terminus (PTS2). PTS2-carrying proteins interact with their cognate receptor protein P...