Development of novel agonists for the orphan nuclear receptor, Nurr1 : a therapeutic strategy for Parkinson’s disease

Parkinson’s Disease (PD) is the second most prevalent neurodegenerative disease among the elderly. It is characterized pathologically by the demise of dopaminergic (DA) neurons in the substantia nigra region of the midbrain resulting in the loss of motor function. The orphan nuclear receptor, Nurr1,...

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Bibliographic Details
Main Author: Toh, Hui Ting
Other Authors: Liu Xuewei
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2019
Subjects:
Online Access:https://hdl.handle.net/10356/89266
http://hdl.handle.net/10220/48045
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Institution: Nanyang Technological University
Language: English
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