Dok3–protein phosphatase 1 interaction attenuates Card9 signaling and neutrophil-dependent antifungal immunity

• المؤلفون الرئيسيون: Loh, Jia Tong, Xu, Shengli, Huo, Jian Xin, Kim, Susana Soo-Yeon, Wang, Yue, Lam, Kong-Peng
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2019
• الموضوعات: Signaling; Antifungal; Science::Biological sciences
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/90011; http://hdl.handle.net/10220/49379

Invasive fungal infection is a serious health threat with high morbidity and mortality. Current antifungal drugs only demonstrate partial success in improving prognosis. Furthermore, mechanisms regulating host defense against fungal pathogens remain elusive. Here, we report that the downstream of ki...