Genetic studies of Prader-Willi patients from Taiwan identify two patients with atypical deletions and provide evidences for conservation of genomic architecture in proximal chromosome 15q

• Main Authors: Lin, Shuan Pei., Ho, Shi Yun., Chen, Yen Jiun., Huang, Chi Yu., Chiu, Hui Ching., Chuang, Chih Kuang., Hou, Aihua., Chen, Jennifer Chi Fung., Lin, Hsiang Yu., Chen, Ken-Shiung.
• 其他作者: School of Biological Sciences
• 格式: Article
• 語言: English
• 出版: 2011
• 主題: DRNTU::Science::Biological sciences::Genetics
• 在線閱讀: https://hdl.handle.net/10356/94104; http://hdl.handle.net/10220/7172
• 機構: Nanyang Technological University

Prader-Willi syndrome (PWS) is a neurogenetic disorder associated with recurrent genomic recombination involving low copy repeats (LCRs) located in the human chromosome 15q11-q13. Previous studies of PWS patients from Asia suggested that there is a higher incidence of deletion and lower incidence of...